CINECA IRIS Institutional Research Information System

IRIS TORINO: [275878] Home page macrotipologia

Sfoglia

Prodotti recenti

Le missioni cattoliche nel secondo Novecento tra nazionalismi postcoloniali e ridefinizione della "missio ad gentes"

Genomic and Transcriptomic Profile of HNF1A-Mutated Liver Adenomas Highlights Molecular Signature and Potential Therapeutic Implications

Hepatocellular adenomas (HAs) are tumors that can develop under different conditions, including in patients harboring a germline mutation in HNF1A. However, little is known about the pathogenesis of such disease. This work aims to better define what mechanisms lie under the development of this condition. Six HAs were sampled from the liver of a 17-year-old male affected by diabetes and multiple hepatic adenomatosis harboring the heterozygous pathogenic germline variant c.815G>A, p.(Arg272His)...

Apoliprotein E-mediated ferroptosis controls cellular proliferation in chronic lymphocytic leukemia

Unraveling vulnerabilities in chronic lymphocytic leukemia (CLL) represents a key approach to understand molecular basis for its indolence and a path toward developing tailored therapeutic approaches. In this study, we found that CLL cells are particularly sensitive to the inhibitory action of abundant serum protein, apolipoprotein E (ApoE). Physiological concentrations of ApoE affect CLL cell viability and inhibit CD40-driven proliferation. Transcriptomics of ApoE-treated CLL cells revealed ...

Circulating cell-free DNA in liver transplantation: A pre- and post-transplant biomarker of graft dysfunction

Liver transplantation (LT) is still limited by organ shortage and post-transplant monitoring issues. While machine perfusion techniques allow for improving organ preservation, biomarkers like donor-derived cell-free DNA (dd-cfDNA) and mitochondrial cfDNA (mt-cfDNA) may provide insights into graft injury and viability pre- and post-LT. Methods. A prospective observational cohort study was conducted on LT recipients (n = 45) to evaluate dd-cfDNA as a biomarker of graft dysfunction during the fi...

Matching clinical and genetic data in pediatric patients at risk of developing cystic kidney disease

Background: Cystic kidney disease is a heterogeneous group of hereditary and non-hereditary pathologic conditions, associated with the development of renal cysts. These conditions may be present both in children and adults. Cysts can even be observed already during the prenatal age, and pediatric patients with cysts need to be clinically monitored. An early clinical and genetic diagnosis is therefore mandatory for optimal patient management. The aim of this study was to perform genetic analys...

Scopri
Tipologia
  • 03-CONTRIBUTO IN RIVISTA154828
  • 02-CAPITOLO DI LIBRO52828
  • 04-CONTRIBUTO IN ATTI DI CONVEGNO41070
  • 07-ALTRO PRODOTTO SCIENTIFICO10859
  • 01-LIBRO9969
  • 05-CURATELA5775
  • 06-BREVETTO551
Autore
  • GULLINO, Maria Lodovica1614
  • MIGLIORE, Ernesto1569
  • SOLANO, Ada Maria1536
  • COSTA, Marco1501
  • AMAPANE, Nicola Carlo1422
  • MONACO, Vincenzo1409
  • GARIBALDI, Angelo1405
  • ROMERO, Alessandra1395
  • SACCHI, Roberto1339
  • BIANCHI, Fabrizio Umberto1315
Data di pubblicazione
  • In corso di stampa416
  • 2020 - 202552779
  • 2010 - 2019108630
  • 2000 - 200977947
  • 1990 - 199924397
  • 1980 - 19899311
  • 1970 - 19792211
  • 1962 - 1969185
Editore
  • -2147
  • Università degli Studi di Torino1847
  • Springer1582
  • Franco Angeli1467
  • Edizioni dell'Orso1299
  • Giappichelli1282
  • UTET1170
  • Il Mulino994
  • Carocci892
  • Elsevier BV:PO Box 211, 1000 AE A...757
Rivista
  • L'INDICE DEI LIBRI DEL MESE1395
  • GIURISPRUDENZA ITALIANA1358
  • PHYSICS LETTERS. SECTION B1206
  • JOURNAL OF HIGH ENERGY PHYSICS810
  • PHYSICAL REVIEW LETTERS773
  • PLOS ONE768
  • STUDI FRANCESI766
  • BLOOD763
  • PROTEZIONE DELLE COLTURE648
  • PHYSICAL REVIEW D, PARTICLES, FIE...609
Serie
  • LECTURE NOTES IN COMPUTER SCIENCE363
  • CEUR WORKSHOP PROCEEDINGS259
  • LECTURE NOTES IN ARTIFICIAL INTEL...150
  • WORKING PAPER SERIES70
  • CARLO ALBERTO NOTEBOOKS58
  • METHODS IN MOLECULAR BIOLOGY49
  • COMMUNICATIONS IN COMPUTER AND IN...32
  • EUROMED ACADEMY OF BUSINESS CONFE...32
  • LECTURE NOTES IN COMPUTER SCIENCE30
  • I LIBRETTI27
Settore disciplinare
  • Settore INF/01 - Informatica67
  • Settore BIO/11 - Biologia Molecolare43
  • Settore FIS/02 - Fisica Teorica, ...34
  • Settore CHIM/02 - Chimica Fisica33
  • Settore CHIM/03 - Chimica General...30
  • Settore SECS-P/07 - Economia Azie...30
  • Settore BIO/13 - Biologia Applicata29
  • Settore CHIM/06 - Chimica Organica29
  • Settore BIO/10 - Biochimica26
  • Settore FIS/01 - Fisica Sperimentale25
Keyword
  • Humans5209
  • Female2629
  • Male2565
  • Middle Aged1473
  • Italy1392
  • Adult1354
  • Aged1253
  • Animals1037
  • COVID-19847
  • Oncology702
Lingua
  • eng151552
  • ita112929
  • fre5185
  • spa2291
  • ger1231
  • por482
  • Italiano481
  • Inglese341
  • rus290
  • lat214
Accesso al fulltext
  • no fulltext153619
  • open59182
  • reserved50554
  • partially open12111
  • embargoed266
  • mixed103
  • restricted43