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Tetraethyl ethenylidenebisphosphonate can undergo facile Michael type addition reaction with simple Grignard reagents to give alkyl, arylalkyl, aryl C-substituted methylene bisphosphonates. This addition easily occurs even if funtionalised Grignard reagents are used.

Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonate

LOLLI, Marco Lucio;LAZZARATO, Loretta;DI STILO, Antonella;FRUTTERO, Roberta;GASCO, Alberto
2002-01-01

Abstract

Tetraethyl ethenylidenebisphosphonate can undergo facile Michael type addition reaction with simple Grignard reagents to give alkyl, arylalkyl, aryl C-substituted methylene bisphosphonates. This addition easily occurs even if funtionalised Grignard reagents are used.
2002
650
77
83
http://scienceserver.cilea.it/cgi-bin/sciserv.pl?collection=journals&journal=0022328x&issue=v650i1-2
Tetraethyl ethenylidenebisphosphonate; Grignard reagents; Michael addition; Bisphosphonates
LOLLI ML; LAZZARATO L; A. DI STILO; FRUTTERO R; GASCO A
03A-Articolo su Rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1164
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