Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.

A general strategy for the obtainment of biodegradable polymer shelled microbubbles as theranostic device

CAVALLI, Roberta;
2013-01-01

Abstract

Fabrication of multifunctional ultrasound contrast agents (UCAs) has been recently addressed by several research groups. A versatile strategy for the synthesis of UCA precursors in the form of biodegradable vesicles with a biocompatible crosslinked polymer shell is described. Upon ultrasound irradiation, acoustic droplet vaporization transforms such particles into microbubbles behaving as UCAs. This proof of concept entails the features of a potential theranostic microdevice.
2013
49
5763
5765
Sabrina Capece; Ester Chiessi; Roberta Cavalli; Dmitry Grishenkov; Gaio Paradossi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/120550
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