Signaling from class I phosphoinositide 3-kinase (PI3K) is often deregulated in leukemia and lymphoma, but which isoforms are involved in T cell acute lymphoblastic leukemia (T-ALL) was not known. In this issue of Cancer Cell, Subramaniam et al. show that T-ALL can be tamed by inhibiting γ and δ PI3K isoforms.

Calming down T cell acute leukemia.

HIRSCH, Emilio;CHIARLE, Roberto
2012

Abstract

Signaling from class I phosphoinositide 3-kinase (PI3K) is often deregulated in leukemia and lymphoma, but which isoforms are involved in T cell acute lymphoblastic leukemia (T-ALL) was not known. In this issue of Cancer Cell, Subramaniam et al. show that T-ALL can be tamed by inhibiting γ and δ PI3K isoforms.
21
449
450
PI3kinase; leucemie.
Hirsch E;Chiarle R
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/130991
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