Endocrine disrupting chemicals (EDCs) have been defined functionally due to their activity on endocrine systems. Much of the attention given to these chemicals arose from the recognition that prenatal exposure to diethylstilbestrol (DES) had long term consequences in women. As more information was collected, it became clear that EDCs had the potential to impact animals across many phyla (8, 9, 10, 38). Furthermore, the exposure of wildlife at field relevant exposures is often at sublethal concentrations, making detection of effects of EDCs challenging, especially when attempting to separate other interacting factors in the animal’s environment. These additional factors may include environmental conditions, food availability, disease, or confounds such as simultaneous exposure to several chemicals. It is therefore important to develop reliable and sensitive measurement end points that are appropriate for the endocrine or organ system that is the target of the EDC.

Neuroendocrine and behavioral consequences of embryonic exposure to endocrine dirupting chemicals

VIGLIETTI, Carla Maria;PANZICA, Giancarlo
2005-01-01

Abstract

Endocrine disrupting chemicals (EDCs) have been defined functionally due to their activity on endocrine systems. Much of the attention given to these chemicals arose from the recognition that prenatal exposure to diethylstilbestrol (DES) had long term consequences in women. As more information was collected, it became clear that EDCs had the potential to impact animals across many phyla (8, 9, 10, 38). Furthermore, the exposure of wildlife at field relevant exposures is often at sublethal concentrations, making detection of effects of EDCs challenging, especially when attempting to separate other interacting factors in the animal’s environment. These additional factors may include environmental conditions, food availability, disease, or confounds such as simultaneous exposure to several chemicals. It is therefore important to develop reliable and sensitive measurement end points that are appropriate for the endocrine or organ system that is the target of the EDC.
2005
Functional Avian Endocrinology
Narosa Publishing House
271
284
9788173195686
http://www.narosa.com/books_display.asp?catgcode=978-81-7319-568-6
OTTINGER M.A.; QUINN M.J.; LAVOIE E.; ABDELNABI M.; THOMPSON N.; HAZELTON J.; MCKERNAN M.; WU J.; HENRY P.; VIGLIETTI-PANZICA C.; PANZICA G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/13439
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