Management of inherited atherogenic dyslipidemias in children

In order to prevent cardiovascular disease the treatment of inherited dyslipidemias in childhood represents an emerging topic capturing scientists consideration. A body of findings emerged in the last decade as for diagnosis and therapy and results were recently summarized to introduce new guidelines by American Academy of Pediatrics and National Institute for Health and Clinical Excellence. It is well known and generally shared the need to detect affected children precociously, when the family history address to genetic dyslipidemia and when premature cardiovascular disease occurs. A spectrum of disorders involving lipoproteins could be recognized by specific biochemical and genetic markers. The availability of a defined diagnosis represents the basis for a correct treatment and follow-up program. This review represents a literature synthesis of main cornerstones and criticisms as for screening program and management of atherogenic inherited dyslipidemias in children and adolescents, are concerned.