AR2p/R1pRatiometric Procedure to Assess Matrix Metalloproteinase-2 Activity by Magnetic Resonance Imaging

Parametric MRI: A paramagnetic gadolinium-loaded liposome for the MRI assessment of the activity of matrix metalloproteinase-2 (MMP-2) is described. The assessment relies on a procedure that involves the ratio R 2p/R1p between the transverse and longitudinal paramagnetic contributions to the water proton relaxation rate. This method is independent of the total gadolinium concentration.

Titolo: AR2p/R1pRatiometric Procedure to Assess Matrix Metalloproteinase-2 Activity by Magnetic Resonance Imaging
Autori Riconosciuti: 
BOFFA, CINZIA  
DASTRU', Walter  
AIME, Silvio  
mostra contributor esterni 
Autori: Valeria Catanzaro;Concetta V. Gringeri;Valeria Menchise;Sergio Padovan;Cinzia Boffa;Walter Dastrù;Linda Chaabane;Giuseppe Digilio;Silvio Aime
Data di pubblicazione: 2013
Abstract: Parametric MRI: A paramagnetic gadolinium-loaded liposome for the MRI assessment of the activity of matrix metalloproteinase-2 (MMP-2) is described. The assessment relies on a procedure that involves the ratio R 2p/R1p between the transverse and longitudinal paramagnetic contributions to the water proton relaxation rate. This method is independent of the total gadolinium concentration.
Volume: 52
Fascicolo: 14
Pagina iniziale: 3926
Pagina finale: 3930
Digital Object Identifier (DOI): 10.1002/anie.201209286
Rivista: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION
Appare nelle tipologie:03A-Articolo su Rivista

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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/2318/140357
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