Immunoassay is one of the most popular analytical methods with widespread applications. However, it presents several drawbacks because of the proteic nature of the antibodies. Molecular imprinting technology has shown a growing ability to prepare artificial molecular recognition systems, with binding properties very similar to those of natural antibodies. This review deals with the application of molecular imprinting technology to immunoassay, with an attention for the state of the art, the current limitations and the possible solutions to these issues
MIP-based immunoassays: state of the art, limitations and perspectives
BAGGIANI, Claudio;ANFOSSI, Laura;GIOVANNOLI, Cristina
2013-01-01
Abstract
Immunoassay is one of the most popular analytical methods with widespread applications. However, it presents several drawbacks because of the proteic nature of the antibodies. Molecular imprinting technology has shown a growing ability to prepare artificial molecular recognition systems, with binding properties very similar to those of natural antibodies. This review deals with the application of molecular imprinting technology to immunoassay, with an attention for the state of the art, the current limitations and the possible solutions to these issues
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