Cytokine-induced killer (CIK) cells are T lymphocytes expanded ex vivo that are endowed with MHC-independent tumoricidal activity. We have recently demonstrated, in a preclinical setting, that CIK cells are active against autologous bone and soft tissue sarcomas. In particular, CIK cells killed a putative sarcoma stem cell population that may underlie disease relapse and chemoresistance.

Activity of cytokine-induced killer cells against bone and soft tissue sarcoma.

SANGIOLO, Dario;AGLIETTA, Massimo;
2014

Abstract

Cytokine-induced killer (CIK) cells are T lymphocytes expanded ex vivo that are endowed with MHC-independent tumoricidal activity. We have recently demonstrated, in a preclinical setting, that CIK cells are active against autologous bone and soft tissue sarcomas. In particular, CIK cells killed a putative sarcoma stem cell population that may underlie disease relapse and chemoresistance.
Mar;3
e28269
2
3
http://www.landesbioscience.com
solid tumors; sarcomas; cancer stem cells; adoptive immunotherapy; CIK cells
Sangiolo D;Mesiano G;Gammaitoni L;Aglietta M;Grignani G
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/148138
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