Background: the impact of narrow band imaging (NBI) in improving the adenoma detection rate (ADR) in a screening scenario is still unclear. Aim: the study aimed to evaluate whether NBI compared with high definition white light high definition colonoscopy (HD-WL) can enhance ADR during screening colonoscopy. Methods: eligible consecutive patients with positive immunologic fecal occult blood test presenting for colonoscopy were included into this randomized controlled study; they were randomly assigned to NBI or HD-WL group. The primary end point was the ADR, secondary aim was the detection rate of advanced adenomas. Results: 237 patients were included in the analysis, of whom 117 were allocated to the NBI arm and 120 to the HD-WL arm. The ADR was not significantly different between the two groups (NBI= 52.1% vs HD-WL= 55%, RR= 0.95, 95% CI 0.75-1.20) as well as the detection rate of advanced adenomas (NBI= 32.5% vs HD-WL= 44.2%, RR= 0.74, 95% CI 0.53-1.02). No significant difference between the proportions of polypoid and flat adenomas was found according to the type of examination. Conclusions: in a screening scenario, NBI did not improve ADR or detection rate of advanced adenomas.

NARROW BAND IMAGING vs HIGH DEFINITION COLONOSCOPY FOR DETECTION OF COLORECTAL ADENOMAS IN PATIENTS WITH POSITIVE FAECAL OCCULT BLOOD TEST: A RANDOMISED TRIAL

RIZZETTO, Mario;SARACCO, Giorgio Maria
2014-01-01

Abstract

Background: the impact of narrow band imaging (NBI) in improving the adenoma detection rate (ADR) in a screening scenario is still unclear. Aim: the study aimed to evaluate whether NBI compared with high definition white light high definition colonoscopy (HD-WL) can enhance ADR during screening colonoscopy. Methods: eligible consecutive patients with positive immunologic fecal occult blood test presenting for colonoscopy were included into this randomized controlled study; they were randomly assigned to NBI or HD-WL group. The primary end point was the ADR, secondary aim was the detection rate of advanced adenomas. Results: 237 patients were included in the analysis, of whom 117 were allocated to the NBI arm and 120 to the HD-WL arm. The ADR was not significantly different between the two groups (NBI= 52.1% vs HD-WL= 55%, RR= 0.95, 95% CI 0.75-1.20) as well as the detection rate of advanced adenomas (NBI= 32.5% vs HD-WL= 44.2%, RR= 0.74, 95% CI 0.53-1.02). No significant difference between the proportions of polypoid and flat adenomas was found according to the type of examination. Conclusions: in a screening scenario, NBI did not improve ADR or detection rate of advanced adenomas.
2014
46
803
807
C. Senore; D. Reggio; A. Musso; M. Bruno; C. De Angelis; C. Giordanino; C. Coppo; R. Tari; M. Pagliarulo; S. Carmagnola; F. Montino; M. Silvani; N. Segnan; M. Rizzetto; G. Saracco
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/148598
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