Shilajit, a herbomineral substance exuded from rocks in steep mountainous regions, has been used for thousands of years by the Indian Ayurvedic and Siddha systems of traditional medicine to relieve ailments and enhance quality of life. Although a large number of therapeutic properties have been ascribed to Shilajit, its therapeutic potential is still largely unexplored by modern research and many of its claimed bioactivities lack scientific validation. The present study was undertaken to investigate the antiviral activity of Shilajit against a panel of viruses including herpes simplex type 1 and 2 (HSV-1, HSV-2), human cytomegalovirus (HCMV), human respiratory syncytial virus (RSV), human rotavirus (HRV), and vesicular stomatitis virus (VSV).

In vitro evaluation of the antiviral properties of Shilajit and investigation of its mechanisms of action

CAGNO, VALERIA;DONALISIO, Manuela
Co-first
;
CIVRA, ANDREA;CAGLIERO, Cecilia Lucia;RUBIOLO, Patrizia;LEMBO, David
Last
2015-01-01

Abstract

Shilajit, a herbomineral substance exuded from rocks in steep mountainous regions, has been used for thousands of years by the Indian Ayurvedic and Siddha systems of traditional medicine to relieve ailments and enhance quality of life. Although a large number of therapeutic properties have been ascribed to Shilajit, its therapeutic potential is still largely unexplored by modern research and many of its claimed bioactivities lack scientific validation. The present study was undertaken to investigate the antiviral activity of Shilajit against a panel of viruses including herpes simplex type 1 and 2 (HSV-1, HSV-2), human cytomegalovirus (HCMV), human respiratory syncytial virus (RSV), human rotavirus (HRV), and vesicular stomatitis virus (VSV).
2015
166
129
134
Antiviral; Ayurvedic medicine; Humic acid; Mechanism of action; Shilajit; Virus
Cagno, Valeria*; Donalisio, Manuela*; Civra, Andrea; Cagliero, Cecilia; Rubiolo, Patrizia; Lembo, David
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1521394
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