The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.

Consensus Paper: Cerebellar Development

LETO, Ketty;BUFFO, Annalisa;PARMIGIANI, ELENA;
2016-01-01

Abstract

The development of the mammalian cerebellum is orchestrated by both cell-autonomous programs and inductive environmental influences. Here, we describe the main processes of cerebellar ontogenesis, highlighting the neurogenic strategies used by developing progenitors, the genetic programs involved in cell fate specification, the progressive changes of structural organization, and some of the better-known abnormalities associated with developmental disorders of the cerebellum.
2016
15
6
789
828
http://link.springer.com/article/10.1007/s12311-015-0724-2/fulltext.html
Cerebellum; Differentiation; Progenitors; Purkinje cells; Specification
Leto, Ketty; Arancillo, Marife; Becker, Esther B. E; Buffo, Annalisa; Chiang, Chin; Ding, Baojin; Dobyns, William B; Dusart, Isabelle; Haldipur, Parthiv; Hatten, Mary E; Hoshino, Mikio; Joyner, Alexandra L; Kano, Masanobu; Kilpatrick, Daniel L; Koibuchi, Noriyuki; Marino, Silvia; Martinez, Salvador; Millen, Kathleen J; Millner, Thomas O; Miyata, Takaki; Parmigiani, Elena; Schilling, Karl; Sekerková, Gabriella; Sillitoe, Roy V; Sotelo, Constantino; Uesaka, Naofumi; Wefers, Annika; Wingate, Richard J. T; Hawkes, Richard
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1526265
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