The clinical outcome of multiple myeloma (MM) is heterogeneous. A simple and reliable tool is needed to stratify patients with MM. We combined the International Staging System (ISS) with chromosomal abnormalities (CA) detected by interphase fluorescent in situ hybridization after CD138 plasma cell purification and serum lactate dehydrogenase (LDH) to evaluate their prognostic value in newly diagnosed MM (NDMM).

Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group

PALUMBO, Antonio
First
;
OLIVA, STEFANIA;CALTAGIRONE, Simona Angela;BRINGHEN, Sara;GAY, Francesca Maria;
2015-01-01

Abstract

The clinical outcome of multiple myeloma (MM) is heterogeneous. A simple and reliable tool is needed to stratify patients with MM. We combined the International Staging System (ISS) with chromosomal abnormalities (CA) detected by interphase fluorescent in situ hybridization after CD138 plasma cell purification and serum lactate dehydrogenase (LDH) to evaluate their prognostic value in newly diagnosed MM (NDMM).
2015
33
26
2863
2869
Palumbo, Antonio; Avet-Loiseau, Hervé; Oliva, Stefania; Lokhorst, Henk M; Goldschmidt, Hartmut; Rosinol, Laura; Richardson, Paul; Caltagirone, Simona; Lahuerta, Juan José; Facon, Thierry; Bringhen, Sara; Gay, Francesca; Attal, Michel; Passera, Roberto; Spencer, Andrew; Offidani, Massimo; Kumar, Shaji; Musto, Pellegrino; Lonial, Sagar; Petrucci, Maria T; Orlowski, Robert Z; Zamagni, Elena; Morgan, Gareth; Dimopoulos, Meletios A; Durie, Brian G M; Anderson, Kenneth C; Sonneveld, Pieter; San Miguel, Jésus; Cavo, Michele; Rajkumar, S Vincent; Moreau, Philippe
File in questo prodotto:
File Dimensione Formato  
Palumbo 2015 - R-ISS for MM - jco.2015.61.2267.pdf

Accesso aperto

Descrizione: Palumbo 2015 - R-ISS for MM - jco.2015.61.2267
Tipo di file: PDF EDITORIALE
Dimensione 241.05 kB
Formato Adobe PDF
241.05 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1526945
Citazioni
  • ???jsp.display-item.citation.pmc??? 716
  • Scopus 1426
  • ???jsp.display-item.citation.isi??? 1288
social impact