The most frequent genetic aberrations in mucosal melanoma are activating mutations of c-KIT. Primary malignant melanomas of esophagus (PMME) are uncommon entities, with aggressive biological behavior and poor prognosis. The better definition of their genotype could improve therapeutic options.
Genetic mutations in primary malignant melanoma of the esophagus: case report and literature review
SANLORENZO, Martina;RIBERO, Simone;OSELLA ABATE, Simona;MARIANI, Sara;STRIGNANO, Paolo;SALIZZONI, Mauro;SAVOIA, Paola;FIERRO, Maria Teresa;QUAGLINO, PietroLast
2022-01-01
Abstract
The most frequent genetic aberrations in mucosal melanoma are activating mutations of c-KIT. Primary malignant melanomas of esophagus (PMME) are uncommon entities, with aggressive biological behavior and poor prognosis. The better definition of their genotype could improve therapeutic options.
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