A chiral derivative of 1,2-benzenedisulfonimide, namely (-) 4,5-dimethyl-3,6-bis(o-tolyl)-1,2-benzenedisulfonimide is herein proven to be an efficient chiral catalysts in a one pot three-component Mannich protocol. Reaction conditions are mild and green, while the enantio and diastereoselectivity are excellent

Brønsted acid catalysed enantio and diastereoselective one-pot three component Mannich reaction

BARBERO, Margherita;CADAMURO, Silvano;DUGHERA, Stefano
2015

Abstract

A chiral derivative of 1,2-benzenedisulfonimide, namely (-) 4,5-dimethyl-3,6-bis(o-tolyl)-1,2-benzenedisulfonimide is herein proven to be an efficient chiral catalysts in a one pot three-component Mannich protocol. Reaction conditions are mild and green, while the enantio and diastereoselectivity are excellent
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http://www.sciencedirect.com/science/article/pii/S0957416615002980
Chiral Brønsted acid, Mannich reaction, Asymmetric counteranion-directed catalysis, Sulfonimides, Three-component reactions.
Barbero, Margherita; Cadamuro, Silvano; Dughera, Stefano
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1531853
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