In this study, chitosan, a commercially-available linear polysaccharide mainly used as antibacterial agent, functional coating and drug-delivery system, is investigated to enlighten both water interactions and its thermal stability by using a set of complementary advanced thermal techniques, rarely applied in polysaccharides characterizations. DSC and TGA, here coupled with FTIR and GCMS analysis of the exhausted gas, were used to reveal thermal events and identify degradation products as a function of the temperature: three main steps in chitosan (N-deacetylation degree, DD = 78%) thermal degradation were highlighted and mechanism proposed. In order to make a comparison with other analogous polymeric systems and validate the results obtained, a medical grade chitosan (DD > 93%) and a commercial chitin were investigated too. Moreover, the water adsorption capacity of chitosan (DD = 78%) was followed by using thermo-microgravimetry (TMG) and the distinction between weight losses of both physically and chemically adsorbed water molecules was achieved. The approach followed allows a complete characterization of the thermal behaviors of the chitosan and highlights the need for complementary advanced thermal techniques in the detailed characterization of complex biopolymers.

Advanced physico-chemical characterization of chitosan by means of TGA coupled on-line with FTIR and GCMS: Thermal degradation and water adsorption capacity

CORAZZARI, INGRID
First
;
NISTICO', ROBERTO;TURCI, Francesco;FRANZOSO, FLAVIA;TABASSO, Silvia;MAGNACCA, Giuliana
2015-01-01

Abstract

In this study, chitosan, a commercially-available linear polysaccharide mainly used as antibacterial agent, functional coating and drug-delivery system, is investigated to enlighten both water interactions and its thermal stability by using a set of complementary advanced thermal techniques, rarely applied in polysaccharides characterizations. DSC and TGA, here coupled with FTIR and GCMS analysis of the exhausted gas, were used to reveal thermal events and identify degradation products as a function of the temperature: three main steps in chitosan (N-deacetylation degree, DD = 78%) thermal degradation were highlighted and mechanism proposed. In order to make a comparison with other analogous polymeric systems and validate the results obtained, a medical grade chitosan (DD > 93%) and a commercial chitin were investigated too. Moreover, the water adsorption capacity of chitosan (DD = 78%) was followed by using thermo-microgravimetry (TMG) and the distinction between weight losses of both physically and chemically adsorbed water molecules was achieved. The approach followed allows a complete characterization of the thermal behaviors of the chitosan and highlights the need for complementary advanced thermal techniques in the detailed characterization of complex biopolymers.
2015
112
1
9
http://www.sciencedirect.com/science/article/pii/S014139101400439X
Biopolymer; Chitosan; Hygroscopic property; Thermal degradation; Water loss
Ingrid Corazzari; Roberto Nisticò; Francesco Turci; Maria Giulia Faga; Flavia Franzoso; Silvia Tabasso; Giuliana Magnacca
File in questo prodotto:
File Dimensione Formato  
2015_Corazzari_PolymDegrStab.pdf

Accesso riservato

Tipo di file: PDF EDITORIALE
Dimensione 1.13 MB
Formato Adobe PDF
1.13 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
2015_Corazzari_PolymDegrStab_OA.pdf

Open Access dal 22/12/2016

Descrizione: Open access
Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 1.5 MB
Formato Adobe PDF
1.5 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/153359
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 389
  • ???jsp.display-item.citation.isi??? 368
social impact