Correcting errors and proofreading are crucial in a post-genomic era, when DNA sequences are already part of an effective medical screening and treatments. SNPs genotyping of complex human genes can lead to questionable associations if not properly handled. Here, we report about a spurious (reitered) association between FCGR2B genetic polymorphisms and systemic lupus erythematosus.

Unfaithful association of FCGR2B genetic polymorphisms with susceptibility to SLE.

BOLLI, ELISABETTA;
2009-01-01

Abstract

Correcting errors and proofreading are crucial in a post-genomic era, when DNA sequences are already part of an effective medical screening and treatments. SNPs genotyping of complex human genes can lead to questionable associations if not properly handled. Here, we report about a spurious (reitered) association between FCGR2B genetic polymorphisms and systemic lupus erythematosus.
2009
42
139
142
http://dx.doi.org/10.1080/08916930802438782
Base Sequence, China; epidemiology, Family, Gene Frequency, Genetic Predisposition to Disease; genetics, Genetics; Population, Genotype, Humans, Lupus Erythematosus; Systemic; epidemiology/genetics, Molecular Sequence Data, Polymorphism; Single Nucleotide, Receptors; IgG; genetics
V. Napolioni;A. Barucca;E. Bolli;A. Concetti;F. M. Venanzi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/153543
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