Men at risk of missed prostate cancer on a negative biopsy often undergo a rebiopsy. We evaluated whether global hypomethylation, measured through LINE-1 methylation, and GSTP1 hypermethylation on a negative biopsy are associated with subsequent prostate cancer diagnosis.
Global Hypomethylation (LINE-1) and Gene-Specific Hypermethylation (GSTP1) on Initial Negative Prostate Biopsy as Markers of Prostate Cancer on a Rebiopsy
ZELIC, RENATA;FIANO, VALENTINA;ZUGNA, DANIELA;GRASSO, CHIARA CELESTINA;DELSEDIME, LUISA;DANIELE, Lorenzo;MERLETTI, Franco;RICHIARDI, Lorenzo
Last
2016-01-01
Abstract
Men at risk of missed prostate cancer on a negative biopsy often undergo a rebiopsy. We evaluated whether global hypomethylation, measured through LINE-1 methylation, and GSTP1 hypermethylation on a negative biopsy are associated with subsequent prostate cancer diagnosis.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
984.full.pdf
Accesso riservato
Tipo di file:
PDF EDITORIALE
Dimensione
518.74 kB
Formato
Adobe PDF
|
518.74 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
