For intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized. Historically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife(®) (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.

Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach

GIAJ LEVRA, Niccolo';
2016-01-01

Abstract

For intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized. Historically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife(®) (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.
2016
16
7
731
740
Brain metastases; Gamma Knife; Linac; radiotherapy approach; stereotactic radiosurgery
Filippo, Alongi; Alba, Fiorentino; Pietro, Mancosu; Pierina, Navarria; Niccolò, Giaj Levra; Rosario, Mazzola; Marta, Scorsetti
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1571894
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