The aim of this study was to evaluate the susceptibility of bacteria, yeasts and viruses to the hydrolate of Coridothymus capitatus (L.) Rchb.f. that contained 0.6% essential oil. Characterization and toxicity were evaluated. The antimicrobial screening was tested against staphylococci (including methicillin-resistant strains), Listeria monocytogenes, Pseudomonas aeruginosa, Candida spp. and Herpes Simplex Virus type 1 (HSV-1) and type 2. Studies on the effects of hydrolate in combination with antimicrobial drugs were performed. Carvacrol was the main compound detected. The hydrolate was non-toxic, and showed the highest antimicrobial activity against S.aureus, C.glabrata and HSV-2. A synergistic effect was obtained between hydrolate and itraconazole (ITZ) against ITZ resistant C.krusei.

Antibacterial, antifungal and antiviral activities of Coridothymus capitatus (L.) RCHB.F. hydrolate from Scoglitty (Sicily)

MANDRAS, Narcisa;SCALAS, Daniela;TULLIO, Viviana Cristina
2015

Abstract

The aim of this study was to evaluate the susceptibility of bacteria, yeasts and viruses to the hydrolate of Coridothymus capitatus (L.) Rchb.f. that contained 0.6% essential oil. Characterization and toxicity were evaluated. The antimicrobial screening was tested against staphylococci (including methicillin-resistant strains), Listeria monocytogenes, Pseudomonas aeruginosa, Candida spp. and Herpes Simplex Virus type 1 (HSV-1) and type 2. Studies on the effects of hydrolate in combination with antimicrobial drugs were performed. Carvacrol was the main compound detected. The hydrolate was non-toxic, and showed the highest antimicrobial activity against S.aureus, C.glabrata and HSV-2. A synergistic effect was obtained between hydrolate and itraconazole (ITZ) against ITZ resistant C.krusei.
147
62
62
http://www.natural1.it/abstracts/item/1918-abstracts-iii-congresso-siroe-2015
Coridothymus capitatus, essential oil, antibacterial, antifungal, antiviral activity
Marino, A; Nostro, A; Mandras, N; Scalas, D; Ginestra, G; Marconi, P; Piovan, D; Miceli, N; Taviano, MF; Filocamo, A; Bisignano, G; Tullio, V
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1573137
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