We describe a case of acute disseminated encephalomyelitis (ADEM) occurring in a three-year old girl with influenza A (H1N1)v infection and manifesting with seizures and ataxia. The brain MRI revealed bilateral hyperintense signal changes in basal ganglia and brain stem. The patient was treated with intravenous methylprednisolone bolus followed by tapering steroids and progressively recovered without neurologic sequelae at the latest follow-up. ADEM may represent a rare postinfectious complication following novel pandemic influenza A H1N1v which should be taken into account in the differential diagnosis of associated neurologic manifestations for the specific therapeutic approach and adequate follow-up.

A case of acute disseminated encephalomyelitis following influenza virus A-H1N1 infection

GARAZZINO, Silvia;GABIANO, CLARA;CALITRI, CARMELINA;AGUZZI, SONIA;BOFFI, Patrizia;
2013-01-01

Abstract

We describe a case of acute disseminated encephalomyelitis (ADEM) occurring in a three-year old girl with influenza A (H1N1)v infection and manifesting with seizures and ataxia. The brain MRI revealed bilateral hyperintense signal changes in basal ganglia and brain stem. The patient was treated with intravenous methylprednisolone bolus followed by tapering steroids and progressively recovered without neurologic sequelae at the latest follow-up. ADEM may represent a rare postinfectious complication following novel pandemic influenza A H1N1v which should be taken into account in the differential diagnosis of associated neurologic manifestations for the specific therapeutic approach and adequate follow-up.
2013
65
5
565
567
Child, Preschool; Encephalomyelitis, Acute Disseminated; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human
Garazzino, S; Gabiano, C; Calitri, C; Zoppo, M; Scolfaro, C; Aguzzi, S; Boffi, P; Vigliano, N; Tovo, P A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1594862
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