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EnglishThe objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of RF and/or ACPA (2 points), and absence of peripheral joint pain (1 point). A score >= 4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score >= 5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients >= 50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated CRP and/or ESR and new hip pain. These criteria are not meant for diagnostic purposes.
2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative / B. Dasgupta; M.A. Cimmino; H. Maradit-Kremers; W.A. Schmidt; M. Schirmer; C. Salvarani; A. Bachta; C. Dejaco; C. Duftner; H.S. Jensen; P. Duhaut; G. Poor; N.P. Kaposi; P. Mandl; P.V. Balint; Z. Schmidt; Annamaria Iagnocco; C. Nannini; F. Cantini; P. Macchioni; N. Pipitone; M.D. Amo; G. Espigol-Frigole; M.C. Cid; V.M. Martinez-Taboada; E. Nordborg; H. Direskeneli; Ahmed K. Aydin Sz; B. Hazleman; B. Silverman; C. Pease; R.J. Wakefield; R. Luqmani; A. Abril; C.J. Michet; R. Marcus; N.J. Gonter; M. Maz; R.E. Carter; C.S. Crowson; E.L. Matteson. - In: ANNALS OF THE RHEUMATIC DISEASES. - ISSN 0003-4967. - 71:4(2012), pp. 484-492.
| Titolo: | 2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative |
| Autori Riconosciuti: | |
| Autori: | B. Dasgupta; M.A. Cimmino; H. Maradit-Kremers; W.A. Schmidt; M. Schirmer; C. Salvarani; A. Bachta; C. Dejaco; C. Duftner; H.S. Jensen; P. Duhaut; G. Poor; N.P. Kaposi; P. Mandl; P.V. Balint; Z. Schmidt; Annamaria Iagnocco; C. Nannini; F. Cantini; P. Macchioni; N. Pipitone; M.D. Amo; G. Espigol-Frigole; M.C. Cid; V.M. Martinez-Taboada; E. Nordborg; H. Direskeneli; Ahmed K. Aydin Sz; B. Hazleman; B. Silverman; C. Pease; R.J. Wakefield; R. Luqmani; A. Abril; C.J. Michet; R. Marcus; N.J. Gonter; M. Maz; R.E. Carter; C.S. Crowson; E.L. Matteson |
| Data di pubblicazione: | 2012 |
| Abstract: | The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of RF and/or ACPA (2 points), and absence of peripheral joint pain (1 point). A score >= 4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score >= 5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients >= 50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated CRP and/or ESR and new hip pain. These criteria are not meant for diagnostic purposes. |
| Volume: | 71 |
| Fascicolo: | 4 |
| Pagina iniziale: | 484 |
| Pagina finale: | 492 |
| Digital Object Identifier (DOI): | 10.1136/annrheumdis-2011-200329 |
| URL: | http://ard.bmj.com/ |
| Parole Chiave: | arthritis; clinical-outcomes; diagnostic uncertainty; erythrocyte sedimentation-rate; features; giant-cell arteritis; guidelines; management; population-based cohort; quality-of-life |
| Rivista: | ANNALS OF THE RHEUMATIC DISEASES |
| Appare nelle tipologie: | 03B-Review in Rivista / Rassegna della Lett. in Riv. / Nota Critica |
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