We evaluated deferasirox pharmacokinetic according to SNPs in genes involved in its metabolism and elimination. Moreover, we defined a plasma area under the curve cut-off value predicting therapy response.
Role of pharmacogenetics on deferasirox AUC and efficacy
CUSATO, JESSICA;ALLEGRA, SARAH;DE FRANCIA, SILVIA;MASSANO, DAVIDE;PIGA, Antonio Giulio;D'AVOLIO, ANTONIO
Last
2016-01-01
Abstract
We evaluated deferasirox pharmacokinetic according to SNPs in genes involved in its metabolism and elimination. Moreover, we defined a plasma area under the curve cut-off value predicting therapy response.
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