An optrode for continuous monitoring of potassium to be used in whole blood was realized. Several commercial chromoionophores have been tried and composition of the membrane has been optimized in order to obtain the highest sensitivity around pH 7.4 and maximum light stability. The sensor is sensitive to pH but a simple equation relates absorbance and the value (pH + log K) and it was used in real experiments with cow whole blood. The analytical range is 1–10 mM of K+ and it matches the clinical requirements.
An optimized optrode for continuous potassium monitoring in whole blood
CAPUTO, Giuseppe;
1999-01-01
Abstract
An optrode for continuous monitoring of potassium to be used in whole blood was realized. Several commercial chromoionophores have been tried and composition of the membrane has been optimized in order to obtain the highest sensitivity around pH 7.4 and maximum light stability. The sensor is sensitive to pH but a simple equation relates absorbance and the value (pH + log K) and it was used in real experiments with cow whole blood. The analytical range is 1–10 mM of K+ and it matches the clinical requirements.
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