Studies on placebo analgesic effects have shown that they can mimic the neurophysiological effects of active medication and can result in subjective pain relief. Classical conditioning and expectancy have been implicated as mechanisms mediating the placebo response. Given that the effects of placebo, psychological treatments, and active medications appear to be mediated by overlapping neurophysiological systems, intricate interactions of pharmacological and psychosocial factors must be assumed to converge at the neurobiological level. Study of the placebo response offers a paradigm and opportunity to study the effect of the psychosocial context per se, placebo treatment, psychotherapy, and active medication effects, thus offering exciting possibilities for improving the healthcare of patients and their ability to obtain the best possible health outcomes.

Conceptualizing placebo as active component and adjunct in psychological treatment

AMANZIO, Martina;PALERMO, SARA
2016

Abstract

Studies on placebo analgesic effects have shown that they can mimic the neurophysiological effects of active medication and can result in subjective pain relief. Classical conditioning and expectancy have been implicated as mechanisms mediating the placebo response. Given that the effects of placebo, psychological treatments, and active medications appear to be mediated by overlapping neurophysiological systems, intricate interactions of pharmacological and psychosocial factors must be assumed to converge at the neurobiological level. Study of the placebo response offers a paradigm and opportunity to study the effect of the psychosocial context per se, placebo treatment, psychotherapy, and active medication effects, thus offering exciting possibilities for improving the healthcare of patients and their ability to obtain the best possible health outcomes.
The Oxford Handbook of Treatment Processes and Outcomes in Psychology. A multidisciplinary biopsychosocial approach
Sara Maltzman
Oxford Library of Psychology
Capitolo 20
407
425
9780199739134
http://www.oxfordhandbooks.com/view/10.1093/oxfordhb/9780199739134.001.0001/oxfordhb-9780199739134
placebo effect, placebo response, expectancy theory, psychotherapy, healthcare
Amanzio M; Palermo S
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1636029
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