A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B (AMB) susceptibility of Aspergillus terreus species complex infections. Three hundred seventy cases from 21 countries were evaluated. The overall prevalence of A. terreus species complex among patients investigated and with mold positive cultures was 5.2% (370/7116). AMB MICs were ranging from 0.125 to 32 mg/L, (median 8mg/L). A. terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high AMB MICs.
A Prospective International Aspergillus terreus Survey: An EFISG, ISHAM and ECMM Joint Study
TULLIO, Viviana Cristina;
2017-01-01
Abstract
A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B (AMB) susceptibility of Aspergillus terreus species complex infections. Three hundred seventy cases from 21 countries were evaluated. The overall prevalence of A. terreus species complex among patients investigated and with mold positive cultures was 5.2% (370/7116). AMB MICs were ranging from 0.125 to 32 mg/L, (median 8mg/L). A. terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high AMB MICs.
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