We retrospectively evaluate the pharmacogenetic role of single nucleotide polymorphisms involved in rifampicin transport (SLCO1B1, MDR1 and PXR genes) and vitamin D (VDR, CYP24A1 and CYP27B1 genes) metabolism and activity on drug plasma and intracellular concentrations.
Role of vitamin D pathway gene polymorphisms on rifampicin plasma and intracellular pharmacokinetics
ALLEGRA, SARAH
Co-first
;FATIGUSO, GIOVANNACo-first
;CALCAGNO, Andrea;BAIETTO, LORENA;MOTTA, ILARIA;FAVATA, FABIO;CUSATO, JESSICA;BONORA, Stefano;DI PERRI, Giovanni;D'AVOLIO, ANTONIOLast
2017-01-01
Abstract
We retrospectively evaluate the pharmacogenetic role of single nucleotide polymorphisms involved in rifampicin transport (SLCO1B1, MDR1 and PXR genes) and vitamin D (VDR, CYP24A1 and CYP27B1 genes) metabolism and activity on drug plasma and intracellular concentrations.
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