In the setting of surveillance for hepatocellular carcinoma (HCC) detection, the use of serum biomarkers in addition to ultrasonography (US) is still a matter of debate. Hence, we performed a meta-analysis to evaluate the diagnostic accuracy of protein induced by vitamin K absence or antagonist-II (PIVKA-II) and alpha-fetoprotein (AFP) alone or in combination for HCC detection in patients at risk of tumor development.

Performance of protein induced by vitamin K absence or antagonist-II assessed by chemiluminescence enzyme immunoassay for hepatocellular carcinoma detection: a meta-analysis

Caviglia, Gian Paolo;Ribaldone, Davide Giuseppe;Abate, Maria Lorena;Ciancio, Alessia;Pellicano, Rinaldo;Smedile, Antonina;Saracco, Giorgio Maria
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2018-01-01

Abstract

In the setting of surveillance for hepatocellular carcinoma (HCC) detection, the use of serum biomarkers in addition to ultrasonography (US) is still a matter of debate. Hence, we performed a meta-analysis to evaluate the diagnostic accuracy of protein induced by vitamin K absence or antagonist-II (PIVKA-II) and alpha-fetoprotein (AFP) alone or in combination for HCC detection in patients at risk of tumor development.
2018
53
6
734
740
Alpha-fetoprotein; hepatocellular carcinoma; meta-analysis; protein induced by vitamin K absence or antagonist-II; surveillance
Caviglia, Gian Paolo; Ribaldone, Davide Giuseppe; Abate, Maria Lorena; Ciancio, Alessia; Pellicano, Rinaldo; Smedile, Antonina; Saracco, Giorgio Maria
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1666707
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