Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26-29 October 2016.

Annual meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic networks in cancer

Porporato PE;
2017

Abstract

Cancers are metabolic entities wherein cancer cells adapt their metabolism to their oncogenic agenda and microenvironmental influences. Metabolically different cancer cell subpopulations collaborate to optimize nutrient delivery with respect to immediate bioenergetic and biosynthetic needs. They can also metabolically exploit host cells. These metabolic networks are directly linked with cancer progression, treatment resistance and relapse. Conversely, metabolic alterations in cancer are exploited for anticancer therapy, imaging and personalized medicine. These topics were addressed at the 3rd annual meeting of the International Society of Cancer Metabolism (ISCaM) in Brussels, Belgium, on 26-29 October 2016.
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http://journal.frontiersin.org/article/10.3389/fphar.2017.00411/full
Cancer imaging; Cancer therapy; Proton dynamics; Tumor metabolism; Tumor microenvironment;
Baldini N.; De Milito A.; Feron O.; Gillies R.J.; Michiels C.; Otto A.M.; Pastorekova S.; Pedersen S.F.; Porporato P.E.; Sonveaux P.; Supuran C.T.; Avnet S.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1678772
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