Microwave Irradiation in Micro- Meso-fluidic Systems; Hybrid Technology has Issued the Challenge

A combination of microwave irradiation and flow chemistry has been described as a promising smart and hyphenated technology that can fuse and synergize the benefits of the techniques. The cells and tissues of all living organisms promote a huge number of bioorganic reactions that occur as flow systems and not the batch-type conditions typically used by chemists and biotechnologists. Microwave-assisted chemical conversion carried out in continuous flow mode with micro- or meso-channel reactors can offer significant processing advantages, including improved thermal exchange, energy efficiency, safety, mixing control, a wider range of reaction conditions, repeatability and scalability as well as dramatic reductions in side-reactions and degradations. This review will discuss relevant examples of organic synthesis and nanoparticles production performed in continuous flow mode with integrated microwave irradiation in micro- or mesofluidic systems.