In the present work, we report on the fabrication of a diamond-based device targeted to the detection of quantal neurotransmitter release. We have developed Multi-electrode Arrays with 16 independent graphitic channels fabricated by means of Deep Ion Beam Lithography (DIBL). These devices are capable of detecting the in vitro exocytotic event from neurosecretory cells, while overcoming several critical limitations of standard amperometric techniques.

Diamond-based multi electrode arrays for monitoring neurotransmitter release

Tomagra, Giulia;Battiato, Alfio;Bernardi, Ettore;Carbone, Emilio;Olivero, Paolo;Carabelli, Valentina;Picollo, Federico
2019-01-01

Abstract

In the present work, we report on the fabrication of a diamond-based device targeted to the detection of quantal neurotransmitter release. We have developed Multi-electrode Arrays with 16 independent graphitic channels fabricated by means of Deep Ion Beam Lithography (DIBL). These devices are capable of detecting the in vitro exocytotic event from neurosecretory cells, while overcoming several critical limitations of standard amperometric techniques.
2019
4th National Conference on Sensors: Proceedings of the Fourth National Conference on Sensors, February 21-23, 2018, Catania, Italy
Springer
539
125
134
978-3-030-04323-0
https://www.springerprofessional.de/en/diamond-based-multi-electrode-arrays-for-monitoring-neurotransmi/16403538
Diamond-based sensor; Electrochemical detection; Ion beam lithography; Neuronal network; Industrial and Manufacturing Engineering
Tomagra, Giulia*; Battiato, Alfio; Bernardi, Ettore; Pasquarelli, Alberto; Carbone, Emilio; Olivero, Paolo; Carabelli, Valentina; Picollo, Federico...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1693560
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