In the present work, we report on the fabrication of a diamond-based device targeted to the detection of quantal neurotransmitter release. We have developed Multi-electrode Arrays with 16 independent graphitic channels fabricated by means of Deep Ion Beam Lithography (DIBL). These devices are capable of detecting the in vitro exocytotic event from neurosecretory cells, while overcoming several critical limitations of standard amperometric techniques.
Diamond-based multi electrode arrays for monitoring neurotransmitter release
Tomagra, Giulia;Battiato, Alfio;Bernardi, Ettore;Carbone, Emilio;Olivero, Paolo;Carabelli, Valentina;Picollo, Federico
2019-01-01
Abstract
In the present work, we report on the fabrication of a diamond-based device targeted to the detection of quantal neurotransmitter release. We have developed Multi-electrode Arrays with 16 independent graphitic channels fabricated by means of Deep Ion Beam Lithography (DIBL). These devices are capable of detecting the in vitro exocytotic event from neurosecretory cells, while overcoming several critical limitations of standard amperometric techniques.
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