The association between iron overload (IO) and risk of cardiovascular disease is controversial. Epidemiological studies have found a significant negative association of transferrin (Tf) saturation and cardiovascular events suggesting that higher body iron possibly confer a protective effect towards developing cardiovascular events. The biological mechanisms of this phenomenon are unknown.
Transferrin Saturation Inversely Correlates with Platelet Function
Barale, Cristina;SENKEEV, ROUSLAN;De Gobbi, Marco;Guerrasio, Angelo;Morotti, Alessandro
Co-last
;Russo, Isabella
2019-01-01
Abstract
The association between iron overload (IO) and risk of cardiovascular disease is controversial. Epidemiological studies have found a significant negative association of transferrin (Tf) saturation and cardiovascular events suggesting that higher body iron possibly confer a protective effect towards developing cardiovascular events. The biological mechanisms of this phenomenon are unknown.
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