Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range of applications. During recent years, one of the most challenging goals is the development of new strategies to finely tune the unique properties of MNPs, in order to improve their effectiveness in the biomedical field. This review provides an up-to-date overview of the methods of synthesis and functionalization of MNPs focusing on Iron Oxide Nanoparticles (IONPs). Firstly, synthesis strategies for fabricating IONPs of different composition, sizes, shapes, and structures are outlined. We describe the close link between physicochemical properties and magnetic characterization, essential to developing innovative and powerful magnetic-driven nanocarriers. In conclusion, we provide a complete background of IONPs functionalization, safety, and applications for the treatment of Central Nervous System disorders.

Magnetic iron oxide nanoparticles: Synthesis, characterization and functionalization for biomedical applications in the Central Nervous System

Ansari S. A. M. K.;Ficiara E.;Ruffinatti F. A.;Stura I.;Argenziano M.;Abollino O.;Cavalli R.;Guiot C.;D'Agata F.
2019-01-01

Abstract

Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range of applications. During recent years, one of the most challenging goals is the development of new strategies to finely tune the unique properties of MNPs, in order to improve their effectiveness in the biomedical field. This review provides an up-to-date overview of the methods of synthesis and functionalization of MNPs focusing on Iron Oxide Nanoparticles (IONPs). Firstly, synthesis strategies for fabricating IONPs of different composition, sizes, shapes, and structures are outlined. We describe the close link between physicochemical properties and magnetic characterization, essential to developing innovative and powerful magnetic-driven nanocarriers. In conclusion, we provide a complete background of IONPs functionalization, safety, and applications for the treatment of Central Nervous System disorders.
2019
12
3
465
465
https://www.mdpi.com/1996-1944/12/3/465/pdf
Biomedical applications; Central nervous system; Iron oxide nanoparticles; Magnetic nanoparticles; Synthesis
Ansari S.A.M.K.; Ficiara E.; Ruffinatti F.A.; Stura I.; Argenziano M.; Abollino O.; Cavalli R.; Guiot C.; D'Agata F.
File in questo prodotto:
File Dimensione Formato  
Materials_2019_Magnetic Iron Oxide_Ansari et al.pdf

Accesso aperto

Descrizione: Pdf Editoriale
Tipo di file: PDF EDITORIALE
Dimensione 5.15 MB
Formato Adobe PDF
5.15 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1711140
Citazioni
  • ???jsp.display-item.citation.pmc??? 48
  • Scopus 179
  • ???jsp.display-item.citation.isi??? 149
social impact