Atrial Fibrillation (AF) may be diagnosed due to symptoms, or it may be found as an incidental electrocardiogram (ECG) finding, or by implanted devices recordings in asymptomatic patients. While anticoagulation, according to individual risk profile, has proven definitely beneficial in terms of prognosis, rhythm control strategies only demonstrated consistent benefits in terms of quality of life. In fact, evidence collected by observational data showed significant benefits in terms of mortality, stroke incidence, and prevention of cognitive impairment for patients referred to AF catheter ablation compared to those medically treated, however randomized trials failed to confirm such results. The aims of this review are to summarize current evidence regarding the treatment specifically of subclinical and asymptomatic AF, to discuss potential benefits of rhythm control therapy, and to highlight unclear areas.

Subclinical and asymptomatic atrial fibrillation: Current evidence and unsolved questions in clinical practice

Saglietto A.;Desalvo P.;Bocchino P.;De Ferrari G.;Anselmino M.
Last
2019

Abstract

Atrial Fibrillation (AF) may be diagnosed due to symptoms, or it may be found as an incidental electrocardiogram (ECG) finding, or by implanted devices recordings in asymptomatic patients. While anticoagulation, according to individual risk profile, has proven definitely beneficial in terms of prognosis, rhythm control strategies only demonstrated consistent benefits in terms of quality of life. In fact, evidence collected by observational data showed significant benefits in terms of mortality, stroke incidence, and prevention of cognitive impairment for patients referred to AF catheter ablation compared to those medically treated, however randomized trials failed to confirm such results. The aims of this review are to summarize current evidence regarding the treatment specifically of subclinical and asymptomatic AF, to discuss potential benefits of rhythm control therapy, and to highlight unclear areas.
55
8
pii: E497
pii: E497
https://www.mdpi.com/1010-660X/55/8/497/pdf
Catheter ablation; Cognitive impairment; Ischemic cerebral events; Screening; Stroke; Subclinical atrial fibrillation
Ballatore A.; Matta M.; Saglietto A.; Desalvo P.; Bocchino P.; Gaita F.; De Ferrari G.; Anselmino M.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1716084
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