Maternal gestational diabetes mellitus (GDM) has been associated with adverse outcomes in the offspring. Growing evidence suggests that the epigenome may play a role, but most previous studies have been small and adjusted for few covariates. The current study meta-analyzed the association between maternal GDM and cord blood DNA methylation in the Pregnancy and Childhood Epigenetics (PACE) consortium.

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

Pizzi, Costanza;
2019-01-01

Abstract

Maternal gestational diabetes mellitus (GDM) has been associated with adverse outcomes in the offspring. Growing evidence suggests that the epigenome may play a role, but most previous studies have been small and adjusted for few covariates. The current study meta-analyzed the association between maternal GDM and cord blood DNA methylation in the Pregnancy and Childhood Epigenetics (PACE) consortium.
2019
43
1
98
105
Howe, Caitlin G; Cox, Bianca; Fore, Ruby; Jungius, James; Kvist, Tuomas; Lent, Samantha; Miles, Harriet E; Salas, Lucas A; Rifas-Shiman, Sheryl; Starl...espandi
File in questo prodotto:
File Dimensione Formato  
31601636.pdf

Accesso aperto

Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 125.13 kB
Formato Adobe PDF
125.13 kB Adobe PDF Visualizza/Apri
Ciliberto - Maternal gestational diabetes mellitus and newborn dna methylation.pdf

Accesso riservato

Tipo di file: PDF EDITORIALE
Dimensione 706.81 kB
Formato Adobe PDF
706.81 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1717632
Citazioni
  • ???jsp.display-item.citation.pmc??? 66
  • Scopus 92
  • ???jsp.display-item.citation.isi??? 83
social impact