To compare the rates of mastectomy and re-operation after breast-conserving surgery (BCS) among patients who had different pre-operative multi-modality imaging, hence identifying significant predictors of mastectomy and re-operations within each group. Method: Retrospective study of consecutive patients with primary breast cancer treated January 2010 – December 2016, divided in 3 groups, undergoing pre-operative local staging respectively with conventional imaging modalities only (2D mammography, ultrasound (US)), conventional imaging and tomosynthesis (DBT) and/or MRI. The primary outcome was identification of significant predictors of surgical outcomes, within each group. Study variables examined in univariate analysis were age, lesion dimension, breast density, multifocality, tumor size, histology, and if associated with outcomes they were included in binary logistic regression analysis. Results: Amongst 1547 patients, patient and tumor characteristics differed across the t...
Preoperative breast cancer staging with multi-modality imaging and surgical outcomes
Durando M.;Campanino P. P.;Bosco D.;Casella C.;Ala A.;Castellano I.;Sapino A.;Bergamasco L.;Fonio P.;
2020-01-01
Abstract
To compare the rates of mastectomy and re-operation after breast-conserving surgery (BCS) among patients who had different pre-operative multi-modality imaging, hence identifying significant predictors of mastectomy and re-operations within each group. Method: Retrospective study of consecutive patients with primary breast cancer treated January 2010 – December 2016, divided in 3 groups, undergoing pre-operative local staging respectively with conventional imaging modalities only (2D mammography, ultrasound (US)), conventional imaging and tomosynthesis (DBT) and/or MRI. The primary outcome was identification of significant predictors of surgical outcomes, within each group. Study variables examined in univariate analysis were age, lesion dimension, breast density, multifocality, tumor size, histology, and if associated with outcomes they were included in binary logistic regression analysis. Results: Amongst 1547 patients, patient and tumor characteristics differed across the t...File | Dimensione | Formato | |
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