In this issue, Grange et al. (2019) show the therapeutic activity of urine-derived EVs in a murine model of acute kidney injury and highlight the presence and indispensable role of the reno-protective factor Klotho carried by uEVs. The regenerative capacity of EVs engineered with human recombinant Klotho is also proposed.
Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model
Grange C.;Papadimitriou E.;Dimuccio V.;Pastorino C.;Molina J.;Camussi G.;Bussolati B.
Last
2020-01-01
Abstract
In this issue, Grange et al. (2019) show the therapeutic activity of urine-derived EVs in a murine model of acute kidney injury and highlight the presence and indispensable role of the reno-protective factor Klotho carried by uEVs. The regenerative capacity of EVs engineered with human recombinant Klotho is also proposed.
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