Anorexia, body wasting, inflammation, muscle, and adipose tissue loss are hallmarks of cancer cachexia, a syndrome that affects the majority of cancer patients, impairing their ability to endure chemotherapeutic therapies and reducing their lifespan. In the last 10 years, alterations of protein turnover and impairment of adult myogenesis have been proposed as major contributing factors.

Interleukin-4 administration improves muscle function, adult myogenesis, and lifespan of colon carcinoma-bearing mice

Penna, Fabio;Costelli, Paola;
2020-01-01

Abstract

Anorexia, body wasting, inflammation, muscle, and adipose tissue loss are hallmarks of cancer cachexia, a syndrome that affects the majority of cancer patients, impairing their ability to endure chemotherapeutic therapies and reducing their lifespan. In the last 10 years, alterations of protein turnover and impairment of adult myogenesis have been proposed as major contributing factors.
2020
1
10
Cancer-induced skeletal muscle atrophy; Interleukin-4; Muscle function; Muscle regeneration; Protein synthesis; Survival curve
Costamagna, Domiziana; Duelen, Robin; Penna, Fabio; Neumann, Detlef; Costelli, Paola; Sampaolesi, Maurilio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1732260
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