During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved the treatment outcome. All of these novel substances differ at least in part in their mode of action from similar drugs of the same drug class, or are representatives of new drug classes, and as such present with very specific side effect profiles. In this review, we summarize these adverse events, provide information on their prevention, and give practical guidance for monitoring of patients and for management of adverse events.

Prevention and management of adverse events of novel agents in multiple myeloma: A consensus of the European Myeloma Network

Gay F.;Boccadoro M.;
2018-01-01

Abstract

During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved the treatment outcome. All of these novel substances differ at least in part in their mode of action from similar drugs of the same drug class, or are representatives of new drug classes, and as such present with very specific side effect profiles. In this review, we summarize these adverse events, provide information on their prevention, and give practical guidance for monitoring of patients and for management of adverse events.
2018
32
7
1542
1560
http://www.nature.com/leu/index.html
Antineoplastic Agents; Disease Management; Drug-Related Side Effects and Adverse Reactions; Humans; Incidence; Molecular Targeted Therapy; Multiple Myeloma; Practice Guidelines as Topic; Risk Assessment
Ludwig H.; Delforge M.; Facon T.; Einsele H.; Gay F.; Moreau P.; Avet-Loiseau H.; Boccadoro M.; Hajek R.; Mohty M.; Cavo M.; Dimopoulos M.A.; San-Miguel J.F.; Terpos E.; Zweegman S.; Garderet L.; Mateos M.-V.; Cook G.; Leleu X.; Goldschmidt H.; Jackson G.; Kaiser M.; Weisel K.; Van De Donk N.W.C.J.; Waage A.; Beksac M.; Mellqvist U.H.; Engelhardt M.; Caers J.; Driessen C.; Blade J.; Sonneveld P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1732840
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