Many factors are associated with recurrence after primary breast-conserving surgery (BCS) and after primary mastectomy; a few data exist on risk factors affecting prognosis after surgery for recurrence. Mastectomy is considered the treatment of choice in patients with breast recurrence after BCS and whole-breast radiation therapy (RT); nevertheless, some authors advocate that in selected cases similar outcomes could be obtained with a second BCS followed by re-RT. In this study, we analyzed how the tumor biology and treatment offered to patients at first recurrence affects long-term prognosis looking for independent risk factors for further recurrences.
A retrospective analysis on 197 cases of breast cancer local recurrence: Biology, treatment, and prognosis
Bounous V. E.First
;Novara L.;Villasco A.;Maggiorotto F.;Biglia N.
Last
2020-01-01
Abstract
Many factors are associated with recurrence after primary breast-conserving surgery (BCS) and after primary mastectomy; a few data exist on risk factors affecting prognosis after surgery for recurrence. Mastectomy is considered the treatment of choice in patients with breast recurrence after BCS and whole-breast radiation therapy (RT); nevertheless, some authors advocate that in selected cases similar outcomes could be obtained with a second BCS followed by re-RT. In this study, we analyzed how the tumor biology and treatment offered to patients at first recurrence affects long-term prognosis looking for independent risk factors for further recurrences.
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