Many factors are associated with recurrence after primary breast-conserving surgery (BCS) and after primary mastectomy; a few data exist on risk factors affecting prognosis after surgery for recurrence. Mastectomy is considered the treatment of choice in patients with breast recurrence after BCS and whole-breast radiation therapy (RT); nevertheless, some authors advocate that in selected cases similar outcomes could be obtained with a second BCS followed by re-RT. In this study, we analyzed how the tumor biology and treatment offered to patients at first recurrence affects long-term prognosis looking for independent risk factors for further recurrences.

A retrospective analysis on 197 cases of breast cancer local recurrence: Biology, treatment, and prognosis

Bounous V. E.
First
;
Novara L.;Villasco A.;Maggiorotto F.;Biglia N.
Last
2020-01-01

Abstract

Many factors are associated with recurrence after primary breast-conserving surgery (BCS) and after primary mastectomy; a few data exist on risk factors affecting prognosis after surgery for recurrence. Mastectomy is considered the treatment of choice in patients with breast recurrence after BCS and whole-breast radiation therapy (RT); nevertheless, some authors advocate that in selected cases similar outcomes could be obtained with a second BCS followed by re-RT. In this study, we analyzed how the tumor biology and treatment offered to patients at first recurrence affects long-term prognosis looking for independent risk factors for further recurrences.
2020
26
5
1096
1098
Breast Cancer, recurrence, prognosis, biology, treatment.
Bounous V.E.; Novara L.; Scicchitano F.; Villasco A.; Maggiorotto F.; Ponzone R.; Biglia N.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1735095
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