Cardiac resynchronization therapy is beneficial in heart failure patients with LVEF ≤35% and electrical dyssynchrony. However, its effects among patients with less severe LV dysfunction have not been established. Recent post-hoc analyses of landmark CRT trials suggest that CRT benefit may be present in patients with LVEF >35% and is associated with improvement in cardiac reverse remodelling, all-cause mortality, and need for heart failure hospitalizations. This review summarizes the currently available literature regarding the potential impact of CRT in patients with more modest reductions in LVEF.

Cardiac resynchronization therapy in heart failure patients with less severe left ventricular dysfunction

DE FERRARI, GAETANO;
2015-01-01

Abstract

Cardiac resynchronization therapy is beneficial in heart failure patients with LVEF ≤35% and electrical dyssynchrony. However, its effects among patients with less severe LV dysfunction have not been established. Recent post-hoc analyses of landmark CRT trials suggest that CRT benefit may be present in patients with LVEF >35% and is associated with improvement in cardiac reverse remodelling, all-cause mortality, and need for heart failure hospitalizations. This review summarizes the currently available literature regarding the potential impact of CRT in patients with more modest reductions in LVEF.
2015
17
2
135
143
Hai OY; Mentz RJ; Zannad F; Gasparini M; DE FERRARI, GAETANO; Daubert J. C; Holzmeister J; Lam Su Ping C; Pochet T; Vincent A; Linde C.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1736562
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