The rabbit has been proposed to represent an animal model that allows studying peripheral nerve regeneration across extended gap lengths. We describe here our experiences with the rabbit median nerve model and the obstacles it comes along with. This short communication is meant to inform the community and to prevent other researcher from investing time and animal lives in a model with low translational power.
Critical analysis of the value of the rabbit median nerve model for biomedical research on peripheral nerve grafts.
Ronchi Giulia
First
;Gambarotta Giovanna;Morano Michela;Fregnan Federica;Tos Pierluigi;Geuna Stefano;
2020-01-01
Abstract
The rabbit has been proposed to represent an animal model that allows studying peripheral nerve regeneration across extended gap lengths. We describe here our experiences with the rabbit median nerve model and the obstacles it comes along with. This short communication is meant to inform the community and to prevent other researcher from investing time and animal lives in a model with low translational power.
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Ronchi_JTERM_2020 pre-print.pdf
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Ronchi_JTissueEngRegenMed_2020.pdf
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