At presentation, isolated metastasis from oropharyngeal squamous cell carcinoma is rare. Liver is a relatively uncommon first site of failure, especially in the absence of other distant metastases, particularly without diagnosis of lung metastases. We report on a case of HPV-related oropharyngeal squamous cell carcinoma with synchronous liver metastasis treated with radiation therapy. This condition, defined as "oligometastatic state," describes a subset of patients with limited volume metastatic disease in whom favorable outcomes were reported with the use of local ablative therapies on both the primary tumor and metastatic sites. As a definitive treatment, we offered the patient, ineligible for other therapeutic approaches, exclusive radiation treatment on the head and neck region and a stereotactic ablative approach targeted to the liver metastasis.

Radiation therapy for oligometastatic oropharyngeal cancer

Arcadipane, Francesca;Franco, Pierfrancesco;Iorio, Giuseppe C;Ricardi, Umberto
2020

Abstract

At presentation, isolated metastasis from oropharyngeal squamous cell carcinoma is rare. Liver is a relatively uncommon first site of failure, especially in the absence of other distant metastases, particularly without diagnosis of lung metastases. We report on a case of HPV-related oropharyngeal squamous cell carcinoma with synchronous liver metastasis treated with radiation therapy. This condition, defined as "oligometastatic state," describes a subset of patients with limited volume metastatic disease in whom favorable outcomes were reported with the use of local ablative therapies on both the primary tumor and metastatic sites. As a definitive treatment, we offered the patient, ineligible for other therapeutic approaches, exclusive radiation treatment on the head and neck region and a stereotactic ablative approach targeted to the liver metastasis.
BJR CASE REPORTS
6
1-20190021
1
6
Martini, Stefania; Arcadipane, Francesca; Franco, Pierfrancesco; Iorio, Giuseppe C; Bartoncini, Sara; Gallio, Elena; Guarneri, Alessia S; Ricardi, Umberto
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1749833
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