Over the past few years, the World Anti-Doping Agency (WADA) has focused its efforts on detecting not only small prohibited molecules, but also larger endogenous molecules such as hormones, in the view of implementing an endocrinological module in the Athlete Biological Passport (ABP). In this chapter, the detection of two major types of hormones used for doping, growth hormone (GH) and endogenous anabolic androgenic steroids (EAASs), will be discussed: a brief historical background followed by a description of state-of-the-art methods applied by accredited anti-doping laboratories will be provided and then current research trends outlined. In addition, microRNAs (miRNAs) will also be presented as a new class of biomarkers for doping detection.

Methods for Doping Detection

Ponzetto F.
First
;
2016-01-01

Abstract

Over the past few years, the World Anti-Doping Agency (WADA) has focused its efforts on detecting not only small prohibited molecules, but also larger endogenous molecules such as hormones, in the view of implementing an endocrinological module in the Athlete Biological Passport (ABP). In this chapter, the detection of two major types of hormones used for doping, growth hormone (GH) and endogenous anabolic androgenic steroids (EAASs), will be discussed: a brief historical background followed by a description of state-of-the-art methods applied by accredited anti-doping laboratories will be provided and then current research trends outlined. In addition, microRNAs (miRNAs) will also be presented as a new class of biomarkers for doping detection.
2016
Frontiers of Hormone Research
S. Karger AG
47
153
167
978-3-318-05868-0
978-3-318-05869-7
Biomarkers; Growth Hormone; Humans; Testosterone Congeners; Doping in Sports
Ponzetto F.; Giraud S.; Leuenberger N.; Boccard J.; Nicoli R.; Baume N.; Rudaz S.; Saugy M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1764994
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