Nineteen patients that had developed hypertrophic scars subsequent to thermal injury were hyped for HLA class II allogenotypes with the restriction fragment length polymorphism technique. A significant association was found with DRβ16 (pc = 1.45 × 10-4; relative risk = 12.25. This finding adds evidence to other data suggesting that immunologic phenomena are involved in pathologic scarring. Moreover, the results presented here have allowed an identification of a genetically determined risk factor for hypertrophic scar formation located in the HLA region. © 1990.
The HLA-DRβ16 allogenotype constitutes a risk factor for hypertrophic scarring
Amoroso A.;
1990-01-01
Abstract
Nineteen patients that had developed hypertrophic scars subsequent to thermal injury were hyped for HLA class II allogenotypes with the restriction fragment length polymorphism technique. A significant association was found with DRβ16 (pc = 1.45 × 10-4; relative risk = 12.25. This finding adds evidence to other data suggesting that immunologic phenomena are involved in pathologic scarring. Moreover, the results presented here have allowed an identification of a genetically determined risk factor for hypertrophic scar formation located in the HLA region. © 1990.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
