We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.

Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report

Bozzali M.;Grassini A.;Morana G.;Zotta M.;Cabras S.;Romagnolo A.;Artusi C. A.;Montalenti E.;Rizzone M. G.;Garbossa D.;Montanaro E.;Lopiano L.
2021-01-01

Abstract

We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.
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COVID-19; Encephalitis; Epilepsy; Focal seizures with impaired awareness
Bozzali M.; Grassini A.; Morana G.; Zotta M.; Cabras S.; Romagnolo A.; Artusi C.A.; Montalenti E.; Rizzone M.G.; Garbossa D.; Montanaro E.; Cercignani M.; Lopiano L.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1788443
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