The fifth annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma was conducted as one of the American Society of Hematology Annual Meeting Scientific Workshops on Thursday December 3, 2020. This workshop focused on four main topics: 1) integrating MRD into clinical trial design and practice; 2) the molecular and immuno-biology of disease evolution and progression in myeloma; 3) adaptation of next generation sequencing, next generation flow cytometry and CyTOF techniques; and 4) chimeric antigen receptor T-cell and other cellular therapies for myeloma. In this report, we provide a summary of the workshop presentations and discuss future directions in the field.

The 2020 BMT CTN Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma

Gay, Francesca;
2021

Abstract

The fifth annual Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma was conducted as one of the American Society of Hematology Annual Meeting Scientific Workshops on Thursday December 3, 2020. This workshop focused on four main topics: 1) integrating MRD into clinical trial design and practice; 2) the molecular and immuno-biology of disease evolution and progression in myeloma; 3) adaptation of next generation sequencing, next generation flow cytometry and CyTOF techniques; and 4) chimeric antigen receptor T-cell and other cellular therapies for myeloma. In this report, we provide a summary of the workshop presentations and discuss future directions in the field.
Online ahead of print.
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https://www.sciencedirect.com/science/article/pii/S2666636721009465?via=ihub
https://doi.org/10.1016/j.jtct.2021.05.027
Cellular therapy; Endpoint, CAR T-cell; Immune profiling; Minimal residual disease; Multiple myeloma
Holstein, Sarah A; Bahlis, Nizar; Bergsagel, P Leif; Bhutani, Manisha; Bolli, Niccolo; Brownstein, Carrie; Demolis, Pierre; Foureau, David; Gay, Francesca; Ghobrial, Irene M; Gormley, Nicole; Hillengass, Jens; Kaiser, Martin; Maus, Marcela V; Melenhorst, J Joseph; Merz, Maximilian; Dwyer, Michael O; Paiva, Bruno; Pasquini, Marcelo C; Shah, Nina; Wong, Sandy W; Usmani, Saad Z; McCarthy, Philip L
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1791012
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