While proton therapy offers an excellent dose conformity and sparing of organs at risk, this can be compromised by uncertainties, e.g. organ motion. This study aimed to investigate the influence of cardiac motion on the contoured oesophagus using electrocardiogram-triggered imaging and to assess the impact of this motion on the robustness of proton therapy plans in oesophageal cancer patients. Limited cardiac-induced motion of the oesophagus was observed with a negligible impact on the robustness of proton therapy plans. Therefore, our data suggest that cardiac motion may be safely ignored in the robust optimisation strategy for proton planning in oesophageal cancer.

A study to investigate the influence of cardiac motion on the robustness of pencil beam scanning proton plans in oesophageal cancer

Levis M.;Ricardi U.;
2020-01-01

Abstract

While proton therapy offers an excellent dose conformity and sparing of organs at risk, this can be compromised by uncertainties, e.g. organ motion. This study aimed to investigate the influence of cardiac motion on the contoured oesophagus using electrocardiogram-triggered imaging and to assess the impact of this motion on the robustness of proton therapy plans in oesophageal cancer patients. Limited cardiac-induced motion of the oesophagus was observed with a negligible impact on the robustness of proton therapy plans. Therefore, our data suggest that cardiac motion may be safely ignored in the robust optimisation strategy for proton planning in oesophageal cancer.
2020
16
50
53
Cardiac motion; Oesophageal cancer; Proton therapy
Thomas M.; Defraene G.; Levis M.; Sterpin E.; Lambrecht M.; Ricardi U.; Haustermans K.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1795779
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