The close relationship between joints and gut inflammation has long been known and several data suggest that dysbiosis could link spondyloarthritis (SpA) to inflammatory bowel diseases (IBD). The introduction of biological drugs, in particular tumour necrosis factor inhibitors (TNFi), revolutionised the management of both these diseases. While the impact of conventional drugs on gut microbiota is well known, poor data are available about TNFi.

Intestinal microbiota changes induced by TNF-inhibitors in IBD-related spondyloarthritis

Borrelli, Richard;Realmuto, Cristina;Caviglia, Gian Paolo;Ribaldone, Davide Giuseppe;Astegiano, Marco;
2021

Abstract

The close relationship between joints and gut inflammation has long been known and several data suggest that dysbiosis could link spondyloarthritis (SpA) to inflammatory bowel diseases (IBD). The introduction of biological drugs, in particular tumour necrosis factor inhibitors (TNFi), revolutionised the management of both these diseases. While the impact of conventional drugs on gut microbiota is well known, poor data are available about TNFi.
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arthritis; autoimmune diseases; spondyloarthritis; tumour necrosis factor inhibitors
Ditto, Maria Chiara; Parisi, Simone; Landolfi, Gianpiero; Borrelli, Richard; Realmuto, Cristina; Finucci, Annacarla; Caviglia, Gian Paolo; Ribaldone, Davide Giuseppe; Astegiano, Marco; Zanetti, Anna; Carrara, Greta; Scirè, Carlo Alberto; Antivalle, Marco; Sarzi-Puttini, Piercarlo; Fusaro, Enrico
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/1800899
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