Targeted therapies have recently changed the approach to advanced melanoma. RAF inhibitors represent the emerging standard of care for metastatic BRAF mutated melanomas. Cutaneous reactions are the most common side effects during vemurafenib treatment, and affect the quality of life. The aim of this study was to provide some practical advices to manage the drug related cutaneous reactions.

Dermatological approach to vemurafenib skin toxicity: a single centre experience

Fava, Paolo;Marra, Elena;Astrua, Chiara;Brizio, Matteo;Cavaliere, Giovanni;Quaglino, Pietro;Fierro, Maria T;Savoia, Paola
2016-01-01

Abstract

Targeted therapies have recently changed the approach to advanced melanoma. RAF inhibitors represent the emerging standard of care for metastatic BRAF mutated melanomas. Cutaneous reactions are the most common side effects during vemurafenib treatment, and affect the quality of life. The aim of this study was to provide some practical advices to manage the drug related cutaneous reactions.
2016
151
1
25
31
Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Dose-Response Relationship, Drug; Exanthema; Female; Humans; Indoles; Keratinocytes; Keratoacanthoma; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Mutation; Photosensitivity Disorders; Proto-Oncogene Proteins B-raf; Risk Factors; Skin Neoplasms; Sulfonamides; Vemurafenib; Warts
Fava, Paolo; Marra, Elena; Astrua, Chiara; Brizio, Matteo; Cavaliere, Giovanni; Quaglino, Pietro; Fierro, Maria T; Savoia, Paola
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/1815350
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